Immunology Lab

Autophagy 16:2020:1021. Induction of autophagy through Clec4e in combination with TLR-4: an innovative strategy to restrict the survival of Mycobacterium tuberculosis. Pahari S, Negi S, Aqdas M, Arnett E, Schlesinger LS, Agrewala JN.

Eur J Immunol. 16:2020:10. Intestinal microbiota disruption limits the isoniazid mediated clearance of Mycobacterium tuberculosis in mice. Negi S, Pahari S, Bashir H,Agrewala JN.

J Proteome Res. 19:2020:4655. Deciphering the structural enigma of HLA class-II binding peptides for enhanced immunoinformatics-based prediction of vaccine epitopes. Chatterjee D, Priyadarshini P, Das DK, Mushtaq K, Singh B,Agrewala JN.

Front Immunol. 11:2020: Gut dysbiosis thwarts the efficacy of vaccine against Mycobacterium tuberculosis. Nadeem S, Maurya SK, Das DK, Khan N, Agrewala JN.

Cancer Immunol Immunother. 68:2019:1995. Predominance of M2 macrophages in gliomas leads to the suppression of local and systemic immunity. Vidyarthi A, Agnihotri T, Khan N, Singh S, Tewari MK, Radotra BD, Chatterjee D, Agrewala JN.

Cancer Medicine 8:2019:246. Low prevalence of anti-xenobiotic antibodies among the occupationally exposed individuals is associated with a high risk of cancer. Sajid M, Agrewala JN.

Front Immunol. 9:2018:1650. TLR-3 stimulation skews M2 macrophages to M1 through IFN-αβ signaling and restricts tumor progression. Vidyarthi A, Khan N, Agnihotri T, Negi S, Das DK, Colegio OR, Tewari MK, Agrewala JN.

J Trans Med. 16:2018:279. A lipidated bi-epitope vaccine comprising of MHC-I and MHC-II binder peptides elicits protective CD4 T cell and CD8 T cell immunity against Mycobacterium tuberculosis. Rai PK, Chodisetti SB, Maurya SK, Nadeem S, Zeng W, Janmeja AK, Jackson DC, Agrewala JN.

J Trans Med. 15:2017:201. A Lipidated peptide of Mycobacterium tuberculosis resuscitates the protective efficacy of BCG vaccine by evoking memory T cell immunity. Rai PK, Chodisetti SB, Zeng W, Nadeem S, Maurya SK, Pahari S, Janmeja AK, Jackson DC, Agrewala JN.

Autoimmunity 7:2017:1. Caerulomycin A suppresses the differentiation of naïve T cells and alleviates the symptoms of experimental autoimmune encephalomyelitis. Kujur W, Gurram RK, Maurya SK, Nadeem S, Chodisetti SB, Khan N, Agrewala JN.

Crit Rev Microbiol. 1:2016:1. T cell exhaustion in tuberculosis: pitfalls and prospects. Khan N, Vidyarthi A, Amir M, Mushtaq K, Agrewala JN.

Crit Rev Microbiol. 4:2015:389. Challenges and Solutions for a Rational Vaccine Design for TB-endemic Regions. Gowthaman U, Mushtaq K, Tan AC, Rai PK, Jackson DC, Agrewala JN.

J Infect Dis. 211:2015: 486-96. Triggering through TLR-2 limits chronically stimulated Th1 cells from undergoing exhaustion. Chodisetti SB, Gowthaman U, Rai PK, Vidyarthi A, Khan N, Agrewala JN.

J Biol Chem. 289:2014:17515-28. Caerulomycin A enhances the TGF-β-Smad3 signalling by suppressing IFN-γ-STAT1 signalling to expand Tregs. Gurram RK, Kujur W, Maurya SK, Agrewala JN.

J Infect Dis. 209:2014:1436-45. Latency Associated Protein Acr1 Impairs Dendritic Cells Maturation and Functionality: A Possible Mechanism of Immune Evasion by Mycobacterium tuberculosis. Siddiqui KF, Amir M, Gurram RK, Khan N, Arora A, K Rajagopal, Agrewala JN.

Transplantation 97:2014:e57-9. Caerulomycin A: a potent novel immunosuppressive agent. Singla AK, Gurram RK, Chauhan A, Khatri N, Vohra RM, Jolly RS, Agrewala JN.

Crit Rev Microbiol. 40:2014:273-280. Friendly Pathogens: Prevent or Provoke Autoimmunity. Sathybama S, Khan N, Agrewala JN.

J Biol Chem. 288: 2013: 29987-99 [IF: 4.8]. Truncated hemoglobin, HbN, is post-translationally modified in Mycobacterium tuberculosis and modulates host-pathogen interactions during intracellular infection. Arya S, Sethi D, Singh S, Hade MD, Singh V, Raju P, Chodisetti SB, Verma D, Varshney GC, Agrewala JN, Dikshit KL.

Trends Mol Medicine 18:2012:607-14. [IF: 11.05]. Lipidated promiscuous peptides vaccine for tuberculosis endemic regions. Gowthaman U, Rai PK, Khan N, Jackson D, Agrewala JN.

PLoS Pathogens 2012 Jun; 8(6):e1002676. [IF: 9.23]. Manipulation of costimulatory molecules by intracellular pathogens: veni, vidi, vici. Khan N, Gowthaman U, Pahari S, Agrewala JN.

J Immunol. 188:2012:5593. [IF: 5.8]. M. tuberculosis modulates macrophage lipid-sensing nuclear receptors PPARγ and TR4 for survival. Mahajan S, Dkhar KH, Chandra V, Dave S, Nanduri R, Janmeja AK, Agrewala JN, Gupta.

J Infect Dis. 204:2011:1328-38. Promiscuous peptide of 16 kDa antigen linked to Pam2Cys protects against tuberculosis by evoking enduring memory T cells response. Gowthaman U, Singh V, Zeng W, Jain S, Siddiqui KF, Chodisetti SB, Gurram RK, Parihar P, Gupta P, Gupta UD, Jackson DC, Agrewala JN.

Crit Rev Microbiol. 37:2011:349-57. Understanding the biology of 16 kDa antigen of Mycobacterium tuberculosis: scope in diagnosis, vaccine design and therapy. Siddiqui KF, Amir M, Agrewala JN.

J Infect Dis. 202:2010:480-9. Coadministration of IL-7 and IL-15 with BCG mount enduring T cell memory response against tuberculosis. Singh V, Gowthaman U, Jain S, Parihar P, Banskar S, Gupta P, Gupta UD, Agrewala JN.

J Proteome Res. 7:2008:154-63. In silico tools for predicting peptides binding to HLA-class II molecules: more confusion than conclusion. Gowthaman U, Agrewala JN.

J Biol Chem. 282:2007:6106-15. Unique ability of activated CD4⁺ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation. Agrewala JN, Brown DM, Lepak NM, Duso D, Huston G, Swain SL.

Immunol Rev. 211:2006:8-22. CD4 memory: generation and multi-faceted roles for CD4 T Cells in protective immunity to influenza. Swain SL, Agrewala JN, Brown D, Gibbs DJ, Golech S, Huston G, Jones S, Kamperschroer C, Lee WH, McKinstry K, Roman E, Strutt T, Weng NP.

J Infect Dis. 190:2004:107-14. Potent role of the vaccines prepared from macrophages infected with live bacteria in protection against tuberculosis and S. typhimurium infections. Sharma N, Agrewala JN.

J Biol Chem. 277:2002:7766-75. Distinct Role of CD80 and CD86 in the regulation of the activation of B cell and B cell Lymphoma. Suvas S, Singh, V, Sahdev, S, Vohra, H, Agrewala, JN.

Eur J Immunol. 29:1999:1753-61. Influence of HLA-DR on the phenotype of CD4⁺ T lymphocytes specific for an epitope of the 16-kD α-crystalline antigen of Mycobacterium tuberculosis. Agrewala JN, Wilkinson RJ.

J Immunol. 160:1998:1067-77. Differential effect of anti-B7-1 and anti-M150 antibodies in restricting the delivery of costimulatory signals from B cells and macrophages. Agrewala JN, Suvas S, Verma RK, Mishra GC.

J Immunol. 153:1994:1613-25. Antigen-specific early primary humoral responses modulate Immunodominance of B cell epitopes. Vijayakrishnan L, Kumar V, Agrewala JN, Mishra GC, Rao KVS.

Eur J Immunol. 24:1994:2092-7. A 150-kDa molecule of murine macrophage membrane stimulates interleukin-2 and interferon-g production and proliferation of ovalbumin-specific CD4⁺ T cells.Agrewala JN, Vinay DS, Joshi A, Mishra GC.