The chemistry department does not offer an undergraduate degree in Chemistry. However, it actively supports the undergraduate programs (B. Tech.) in Computer Science and Engineering, Electrical Engineering, and Mechanical Engineering at the institute. All undergraduate students of this institute are required to do two core courses and a course in Environmental Science and Engineering. Based on their preferences, students may choose one or more electives under the open electives category. The coordinator for the undergraduate program is Dr. Prabal Banerjee.
CY101 Chemistry for Engineers, 4 (3-1-2-5-4)
Quantum Mechanical principles of structure and bonding in molecules. Reaction rates. Free energy and entropy changes in chemical processes. EMF of galvanic cells, Liquid junction potential. Structure and stereoisomerism. Conformational analysis. Reactivity-acids and bases. Kinetic and thermodynamic criteria of reactions. Electrophilic and nucleophilic substitution reactions. Elimination reactions. Determination of mechanism. Transition metal complexes-crystal field theory, electronic spectra and magnetism. Organometallics-EAN rule, metal carbonyls, metallocenes. Inorganic solid-structure and applications.
Integrated course with an emphasis on experiment design. Focus on measurement techniques and the interpretation of results.
CY230 Introduction to Organic Chemistry and Biochemistry (Chemical Engineering Students only)
GE111 Introduction to Environmental Science and Engineering, 3 (3-1-0-6-3)
Atmosphere, Composition & Behavior: Gaseous & particulate constituents of the atmosphere, temperature and pressure profile of atmosphere, Atmospheric Photochemistry: Electromagnetic radiations, kinetics of thermal and photochemical processes, Reactions in the upper atmosphere, photo processes in the troposphere, photochemical smog, photosynthesis, Ozone chemistry. Green Chemistry: Principle and applications, green chemical industrial process, sustainable fuel for automobiles and power generation. Air pollution: Standards, effect of air pollutants, origin and fate of air pollutants, atmospheric dispersion, and air pollution control at stationary and mobile sources
CY Materials Chemistry
Synthesis of molecular, non molecular and composite materials. Characterization techniques. Structure property relationships. Applications-Clean energy, environmental remediation.
CY Measuring Molecules Prerequisite: CYL101
Spectrosocopy-Radiation matter interactions: UV-Vis: The electromagnetic spectrum, Brief introduction of Emission and Absorption spectra, Ultraviolet and visible radiation, Electronic transitions and the UV spectrum, The Beer-Lambert Law (and deviations from it), Chromophores, conjugation, and auxochromes, Selection rules, Empirical rules for calculating absorption maxima, Shifts in absorption maxima (intensity and wavelength), Steric effects in UV spectra, Light sources, Solution preparation and choice of solvent, Unknown compounds identification. IR: Theory, Bond properties & absorption trends, Mode of Stretching & Bending, Fourier Transformation Spectroscopy, Characteristic group absorptions of organic compounds, Data analysis, Sample preparation. NMR: Nuclear spin state, Magnetic Momentum, Absorption of energy & Mechanism of Absorption (resonance), Population density in nuclear spin state, chemical shift and shielding, Brief introduction of Continuous-Wave (CW) and Pulsed Fourier Transformation, Integration, Local diamagnetic shielding (Electronegativity, Hybridization effects & exchangeable protons), Magnetic Anisotropy, Spin-Spin splitting, Pascal’s Triangle, Coupling constant, brief introduction of 13C NMR, Data analysis with the help of 1H & 13C NMR spectra.
CYL240 Chemistry of Life-An Introduction
Cell: prokaryotic and eukaryotic cell structure, major cell organelles and their function, cell membrane and its function including cell signalling, cell cycle, and programmed cell death. Biomolecules: structure and function of carbohydrates, lipids, nucleic acids, and proteins. Enzymes: classification based on their structure, role as biocatalysts, and enzyme inhibition. Vitamins: types and functions, and their role as coenzymes. Nucleic acids: understanding DNA as a hereditary material, structures of DNA and RNA, concept of gene and genome, basic outline of the central dogma, concepts of replication, transcription, and translation, mutations, viruses, an overview of genetic engineering/biotechnology (recombinant DNA/hybridoma), polymerase chain reaction (PCR), and DNA sequencing. Metabolism: ATP and energy generation, outline of glycolysis, β-oxication, the TCA cyle, de-animation, and the urea cycle.
CY457 Theoretical Chemistry
Born-Oppenheimer approximation, Semi-empirical and Ab initio methods, Molecular dynamics, Variational methods, Hartree-Fock approximations, Self-consistent field method, Restricted and unrestricted Hartree-Fock, Gaussian- and Slater basis functions, Hartree-Fock-Roothaan method, Correlations: Many-body perturbation theory, Configuration interaction and Coupled-Cluster methods, Density-functional theory: Local density approximation (LDA), Hybrid methods, The Mulliken charges, Orbital population, Vibration analysis,Potential energy surfaces and Quantum dynamics, Plane wave formalism.
Pre-requisite: CY101; Basic understanding of cells, tissues, and proteins (optional)
Biomaterials, bulk and surface properties of biomaterials and their influence on tissue interface dynamics, classes of biomaterials used in medicine (metals, ceramics, composites, polymers, hydrogels / gels, and biologics), biodegradable biomaterials. Protein adsorption to surfaces, cell and tissue interaction with biomaterials, host responses to biomaterials (inflammation, immunity, systemic toxicity, hypersensitivity, blood coagulation, and tumoriegenesis), concept of biocompatibility. Testing biomaterials in vitro and in vivo. Application of biomaterials in medicine (soft and hard tissue replacement, and drug delivery)
CY459 Biomedical Nanotechnology
Pre-requisite: Basic understanding of organic reaction mechanism, stereochemistry of carbon compounds, biomolecules, cells and tissues.
Biomedical Nanotechnology: An introduction to nanotechnology; fabrication and characterization of nanomaterials; quantum dot, carbon-based, magnetic, polymer-based , and bio nanomaterials; advantages of using nanoscale materials; biomedical nanotechnology Biomedical Nanotechnology in Diagnostics: High through put screening (HTPS) and diagnostics; point-of-care (POC) diagnostics; arrays; nanoparticle, quantum-dot, silicon nanowire-based detection systems; DNA biochips; label-free detection. Biomedical Nanotechnology in Therapeutics: Drug delivery; use of quantum dots, carbon nanotubes, and nanoparticles in therapy; polymeric nanoparticles and spheres; polymeric nanoparticles in photodynamic therapy; polymer therapeutics; liposomes; growth of neurons on nanomaterials; nanomaterials for brain protection and repair; nanorobotics for surgery. Biomedical Nanotechnology in Cancer Treatment: Rationale for using nanotechnology in cancer therapy; examples of abraxane and doxil; passive tumor targeting by enhanced permeability and retention effect; active targeting strategies in cancer therapy; multifunctional nanoparticles in cancer therapy; theranostics. Biomedical Nanotechnology in Implants and Prostheses: Implants and prostheses; reconstructive Intervention; biomaterials and biocompatibility; an overview on methods currently used for nanofabrication of implants
Potential risks: Toxicities of nanoparticles and carbon nanotubes; FDA approval, clinical trials, and regulatory pathways for nanoparticle therapeutics.