Manoj Pandey

Profile Image: 
Dr. Manoj Kumar Pandey
Room & Contact: 

Office: Room 239C (Transit campus)

Phone: 01881-242318

Designation: 

Assistant Professor

Department: 

Department of Chemistry

Email: 

mkpandey@iitrpr.ac.in

Biography: 

Manoj obtained his M.Sc. and Ph.D. degrees in Chemistry from the Indian Institute of Technology Madras. His Ph.D. work mainly focused on the development of theoretical frameworks/models to solve time-dependent spin Hamiltonians in magnetic resonance. In the post-doctoral research work at the University of Michigan, Ann Arbor (USA), he carried out experimental and theoretical nuclear magnetic resonance (NMR) studies on membrane proteins and peptides. Prior to joining IIT Ropar, he worked towards the development of proton-based methods under very fast magic angle spinning (MAS) and high magnetic field at RIKEN, Yokohama, Japan.

Areas of Research: 

Analytic theory of time-dependent spin interactions

Development of recoupling and decoupling-based experimental NMR methods

Structural and dynamics studies of chemical and biological solids

Quantum Chemical Calculations of NMR structural parameters

Education: 

Ph.D. (Chemistry): Indian Institute of Technology Madras (2005 - 2010)

M.Sc. (Chemistry): Indian Institute of Technology Madras (2002 - 2004)

B.Sc. (Chemistry): Banaras Hindu University (1999 - 2002)

Selected Publications/Patents: 

Group Members

Ph.D. Scholars

  1. Ekta (Aug 2018 - present)
  2. Neelam (Aug 2018 - present)

Project Student

  1. Sunil Kumar (Oct 2019 - present)

M.Sc. Project Student

  1. Ekta (2017 - 2018)

 

Selected Publications

1. Pandey, M. K., Damron, J. T., Ramamoorthy, A., Nishiyama, Y. (2019) Proton-detected 3D 1H anisotropic/14N/1H isotropic chemical shifts correlation NMR under fast magic angle spinning on solid samples without isotopic enrichment, Solid State Nucl. Magn. Reson. 97, 40-45.

2. Pandey, M. K., Nishiyama, Y. (2018) A one-dimensional solid-state NMR approach for 14NH/14NH overtone correlation through 1H/1H mixing under fast MAS, Phys. Chem. Chem. Phys., 20, 25849-25853. 

3. Tolchard, J., Pandey, M. K., Berbon, M., Noubhani, A., Saupe, S. J., Nishiyama, Y., Habenstein, B., Loquet. A. (2018) Detection of side-chain proton resonances of fully protonated biosolids in nano-litre volumes by magic angle spinning solid-state NMR, J. Biomol. NMR, 70, 177-185.

4. Damron, J. T., Kersten, K. M., Pandey, M. K., Mroue, K., Reddy, J. Y., Nishiyama, Y., Matzger, A., Ramamoorthy, A. (2017), Electrostatic Constraints Assessed by 1H MAS NMR Illuminate Differences in Crystalline Polymorphs, J. Phys. Chem. Letters. 8 (17), 4253-4257.

5. Malon, M., Pandey, M. K., Nishiyama, Y. (2017) Revealing the Local Proton Network through Three-Dimensional 13C/1H Double Quantum/1H Single Quantum and 1H Double Quantum/13C/1H Single Quantum Correlations Fast MAS Solid-State NMR Spectroscopy at Natural Abundance, J. Phys. Chem. B, 121(34), 8123-8131. 

6. Rajput, L, Banik, M, Yarava, J.R., Sumy, J., Pandey, M. K., Nishiyama, Y., Desiraju, G. R. (2017) Exploring salt-cocrystal continuum with solid-state NMR using natural abundance samples: implications for crystal engineering, IUCrJ, 4, 466-475 

7. Pandey, M. K., Amoureux, J-P., Asakura, T., Nishiyama, Y. (2016) Sensitivity enhanced 14N/14N correlations to probe inter beta-sheet interactions using fast magic angle spinning solid-state NMR in biological solids, Phys. Chem. Chem. Phys. 18, 22583-22589.

8. Pandey, M. K., Yarava, J.R, Zhang, R., Ramamoorthy, A., Nishiyama, Y., (2016), Proton-detected 3D 15N/1H/1H isotropic/anisotropic/isotropic chemical shift correlation solid-state NMR at 70 kHz MAS, Solid State Nucl. Magn. Reson. 76-77: 1–6.

9. Pandey, M.K., Kato, H., Ishii, Y., Nishiyama, Y., (2016), Two-dimensional Proton-detected 35Cl/1H correlation Solid-State NMR Experiment under Fast Magic Angle Sample Spinning: Application to Pharmaceutical compounds, Phys. Chem. Chem. Phys. 18, 6209-6216.

10. Pandey, M. K., Nishiyama, Y., (2015), Determination of NH Proton Chemical Shift Anisotropy with 14N-1H Heteronuclear Decoupling using Ultrafast Magic Angle Spinning Solid-State NMR, J. Magn. Reson., 261, 133-140.

11. Robertson A, J., Pandey, M. K., Marsh, A., Nishiyama, Y., Brown, S. P. (2015), The use of a selective saturation pulse to suppress t1 noise in two-dimensional 1H fast magic angle spinning solid-state NMR spectroscopy, J. Magn. Reson., 260, 89-97. 

12. Pandey, M. K., Nishiyama, Y., (2015), Proton-detected 3D 14N/14N/1H isotropic shift correlation experiment mediated through 1H-1H RFDR mixing on a natural abundant sample under Ultrafast MAS, J. Magn. Reson., 258, 96-101. 

13. Pandey, M. K., Nishiyama, Y., (2015) Determination of Relative Orientation between 1H CSA tensors from a 3D Solid-State NMR Experiment mediated through 1H/1H RFDR mixing under Ultrafast MAS, Solid State Nucl. Magn. Reson., 70, 15-20.

14. Pandey, M. K., Malon, M., Ramamoorthy, A., Nishiyama, Y., (2015) Composite-180° Pulse-Based Symmetry Sequences to Recouple Proton Chemical Shift Anisotropy Tensors under Ultrafast MAS Solid-State NMR Spectroscopy, J. Magn. Reson. 250, 45-54. 

15. Pandey, M. K., Vivekanandan, S., Yamamoto, K., Im, S-C., Waskell, L., Ramamoorthy, A., (2014) Proton-detected 2D radio frequency driven recoupling solid-state NMR studies on micelle-associated cytochrome-b5, J. Magn. Reson., 242, 169-179.

16. Higashi, K., Yamamoto, K., Pandey, M. K., Mroue, K. H., Moribe, K., Yamamoto, K., Ramamoorthy, A. (2014) Insights into Atomic-level Interaction between Mefenamic Acid and Eudragit® EPO in Supersaturated Solution by Magic Angle Spinning Solid-State NMR Spectroscopy, J. Molec. Pharm., 11, 351-357.

17. Pandey, M. K., Vivekanandan, S., Ahuja, S., Huang, R., Im, S-C.,  Waskell, L., Ramamoorthy, A., (2013) Cytochrome-P450-Cytochrome-b5 interaction in a membrane environment changes 15N Chemical Shift Anisotropy Tensors, J. Phys. Chem. B, 117, 13851-13860.

18. Pandey, M. K., Qadri, Z., Ramachandran, R., (2013) Understanding cross-polarization (CP) NMR experiments through dipolar truncation, J. Chem. Phys., 138, 114108.

19. Pandey, M. K., Ramamoorthy, A., (2013) Quantum Chemical Calculations of Amide-15N Chemical Shift Anisotropy Tensors for a Membrane-Bound Cytochrome‑b5, J. Phys. Chem. B, 117, 859-867.

20. Pandey, M. K., Vivekanandan, S., Ahuja, S., Pichumani, K., Im, S-C., Waskell, L., Ramamoorthy, A., (2012) Determination of 15N Chemical Shift Anisotropy from a Membrane-Bound Protein by NMR Spectroscopy, J. Phys. Chem. B, 116, 7181-7189.

21. Pandey, M. K., Ramachandran, R., (2011) Operator-based analytic theory of decoherence in NMR, Molec. Phys., 109, 1545-1565.

22. Pandey, M. K., Krishnan, M. S., (2010) Effective Floquet Hamiltonians for dipolar and quadrupolar coupled N-spin systems in the solid state NMR under magic angle spinning J. Chem. Phys., 133, 174121.

23.  Pandey, M. K., Ramachandran, R., (2010) A theoretical perspective on the accuracy of Rotational Resonance (R2) based distance measurements in solid-state NMR, Molec. Phys., 108, 619-635.

Sponsored Project

Ongoing
        
        Sponsor: SERB-DST, New Delhi
        Title: Development of theoretical models to describe 14N-1H decoupling in solid-state NMR
        Duration: 3 years (Sep 2017 - Sep 2020), PI
Work Experience: 

Assistant Professor (Dec 2016 - present): IIT Ropar

Research Scientist (Apr 2016 - Dec 2016): JEOL RESONANCE Inc., Akishima, Tokyo, Japan

Research Scientist (June 2014 - Mar 2016): RIKEN, Yokohama, Japan

Postdoctoral Fellow (Mar 2011 - Feb 2014): Department of Biophysics and Chemistry, University of Michigan, Ann Arbor