Publications

V Chawla, S Roy, J Raju, P Bundel, D Pal, Y Singh (2025); Proangiogenic Cyclic Peptide Nanotubes for Diabetic Wound Healing, ACS Applied Bio Materials, 8 (4), 2787-2799(IF: 4.7)

Banerjee, D., Patra, D., Sinha, A., Chakrabarty, D., Patra, A., Sarmah, R., Dey, U., Dutta, R., Bhagabati, S. K., Mukherjee, A. K., Kumar, A., Pal, D., & Dasgupta, S. (2024); Macrophage foam cell-derived mediator promotes spontaneous fat lipolysis in atherosclerosis models, Journal of Leukocyte Biology, qiae210. (IF: 3.4)

K. Bhavya, K. Agarwal, D. Negi, K. Niveria, Y. Singh, A. Verma, S. Dasgupta, N. Nirmalkar, D. Pal*, Oxygen Nanobubbles Halt Tumor Aggression and Metastasis by Inhibiting Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Lung and Mammary Adenocarcinoma, ACS Applied Nano Materials, 7 (21), 25198-25211 (IF: 5.3)

A. Mallick, B. Basumatary, M. Kumar, K. Arora, D. Pal, A. Sahani. Performance Evaluation of Neonatal Anti-Pressure Ulcer Bed Using a Novel Force-Sensing Array, Journal of Medical Devices, 2024

G. Singh, M. Mittal, J. Singh, AS Gill, K. Bhavya, D. Pal. Enhancing the performance of reinforced hydroxyapatite coatings through post coating treatment, Results in Surfaces and Interfaces, 2024

D. Negi, K. Bhavya, D. Pal, Y. Singh*. Acemannan coated, cobalt-doped biphasic calcium phosphate nanoparticles for immunomodulation regulated bone regeneration , Biomaterial Sciences 2024 (IF: 5.8 )

D. Patra, P. Ramprasad, S. Sharma, U. Dey, V.Kumar, S. Singh, S. Dasgupta, A. Kumar, K. Tikoo, D. Pal*. Adipose tissue macrophage-derived microRNA-210-3p disrupts systemic insulin sensitivity by silencing GLUT4 in obesity Journal of Biological Chemistry  2024 (IF: 5.48)

S. Mazumder, A. Sinha, S. Ghosh, G.C. Sharma, B.M. Prusty, D. Manna, D. Pal, C.Pal, S. Dasgupta. Leishmania LPG interacts with LRR5/LRR6 of macrophage TLR4 for parasite invasion and impairs the macrophage functions. Pathogens and Disease  2023 (IF: 3.5)

D. Patra, D. Banerjee, P. Ramprasad, S.Roy, D. Pal*, S. Dasgupta* (2023) Recent insights of obesity-induced gut and adipose tissue dysbiosis in type 2 diabetes; Frontiers in Molecular Bioscience DOI: https://doi.org/10.3389/fmolb.2023.1224982 (IF: 6.11)

S. Roy, M. Halder, P Ramprasad, S Dasgupta, Y. Singh*, D Pal* (2023) Oxidized pullulan exhibits potent antibacterial activity against S. aureus by disrupting its membrane integrity; International Journal of Biological Macromolecules DOI: 10.1016/j.ijbiomac.2023.126049 (IF: 8.2)

D. Patra, D. Pal* (2023) Macrophage derived miR-210-3p causes adipocyte insulin resistance in obesity. Diabetes Technology & Therapeutics. DOI: 10.1089/dia.2023.2525.abstracts (IF: 7.337)

D. Pal, S. Ghatak, K. Singh, A. S. Abouhashem, M. Kumar, M S El Masry, SK. Mohanty, R. Palakurti, Y. Rustagi, S. Tabasum, DK. Khona, S. Khanna, S. Kacar, R. Srivastava, P. Bhasme, S S. Verma, E. Hernandez, A. Sharma, D. Reese, P. Verma, N. Ghosh, M. Gorain, J. Wan, S. Liu, Y. Liu, NH Castro, SC. Gnyawali, W. Lawrence, J Moore, DG. Perez, S. Roy, MC. Yoder & CK. Sen (2023) Identification of a physiologic vasculogenic fibroblast state to achieve tissue repair. Nature communications. DOI: 10.1038/s41467-023-36665-z. (IF:17.69)

D. Patra, S. Roy, L. Arora, S.W. Kabeer, S. Singh, U. Dey, D. Banerjee, A. Sinha, S. Dasgupta, K. Tikoo, A. Kumar, & D. Pal* (2022). miR-210-3p promotes obesity-induced adipose tissue inflammation and insulin resistance by targeting SOCS1 mediated NF-κB pathway. Diabetes. DOI: 10.2337/db22-0284  (IF: 9.332)

L. Arora, M. Kalia, S. Roy, & D. Pal* (2022). Assessment of Mitochondrial Health in Cancer-Associated Fibroblasts Isolated from 3D Multicellular Lung Tumor Spheroids. Journal of Visualized Experiments: Jove, (188). DOI: 10.3791/64315 (IF: 1.355)

K Singh, Y Rustagi, AS Abouhashem, S. Tabasum, P Verma, E Hernandez, D. Pal, DK Khona, SK Mohanty, M Kumar, R Srivastava, PR Guda, SS Verma, S Mahajan, JA Killian, LA Walker, S Ghatak, SS Mathew-Steiner, KE Wanczyk, S Liu, J Wan, P Yan, R Bundschuh, S Khanna, GM Gordillo, MP Murphy, S Roy & CK Sen (2022) Genome-wide DNA hypermethylation opposes healing in chronic wound patients by impairing epithelial-to-mesenchymal transition   J Clinical Investigation.  DOI: 10.1172/JCI157279. (IF: 19.456)

L. Arora, M. Kalia, S. Dasgupta, N. Singh,  A.K. Verma, and D. Pal*. (2022) Development of a Multicellular 3D Tumor Model to Study Cellular Heterogeneity and Plasticity in NSCLC Tumor Microenvironment. Frontiers in Oncology. 12:881207. DOI: 10.3389/fonc.2022.881207 (IF: 5.738)

L. Arora, D. Patra, S. Roy, S. Nanda, N. Singh, A.K. Verma, A. Chakraborti, S. Dasgupta, D. Pal* (2022) Hypoxia-induced miR-210-3p expression in lung adenocarcinoma potentiates tumor development by regulating CCL2-mediated monocyte infiltration.  Molecular Oncology  (in press) (IF: 7.449)

D. Banerjee‡, D. Patra‡, A. Sinha, S. Roy, R. Pant, R. Sarmah, R. Dutta, S.K. Bhagabati, K. Tikoo, D. Pal* & S. Dasgupta*. (2022). Lipid-induced monokine Cyclophilin-A promotes adipose tissue dysfunction implementing insulin resistance and type 2 diabetes in zebrafish and mice models of obesity. Cellular and Molecular Life Sciences 79,282. (IF: 9.207) (‡equal contributor)

B. Kumari‡, M. Mantipally‡, S. Roy, L. Arora, V.N. Badavath, M. Gangireddy, S. Dasgupta, R. Gundla*, & D. Pal*. (2022). Novel imidazo [1, 2-a] pyridine derivatives induce apoptosis and cell cycle arrest in non-small cell lung cancer by activating NADPH oxidase mediated oxidative stress. Life Sciences, p.120334. (IF: 6.780) (‡equal contributor)

2018-2021

D. Banerjee, A. Sinha, S. Saikia, B. Gogoi, A.K. Rathore, A.S. Das, D. Pal, A.K. Buragohain, S. Dasgupta (2018) Inflammation induced mTORC2-Akt-mTORC1 signaling promotes macrophage foam cell formation. Biochimie151: 139-149 (IF: 4.079).

N. Chauhan, P. Gupta, L. Arora, D. Pal, & Y. Singh (2021). Dexamethasone-loaded, injectable pullulan-poly (ethylene glycol) hydrogels for bone tissue regeneration in chronic inflammatory conditions. Materials Science and Engineering: C, 130, 112463. (IF: 7.328)

L. Arora, D. Pal* (2021) Remodeling of Stromal Cells and Immune Landscape in Microenvironment During Tumor Progression. Frontiers in Oncology Mar 8;11:596798.  doi: 10.3389/fonc.2021.596798. (IF: 6.24)

B. Rawat, K.K. Mishra, U. Barman, L. Arora, D. Pal, and R. Paily (2020) Two-Dimensional MoS2-based Electrochemical Biosensor for Highly Selective Detection of Glutathione. IEEE Sensor Journal,20(13):6937-6944. (IF: 3.076)

K. Singh, M. Sinha, D. Pal, S. Tabasum, S.C. Gnyawali, D. Khona, S. Sarkar, S.K. Mohanty, F.S. Gonzalez, S. Khanna, S. Roy, C.K. Sen (2019) Cutaneous Epithelial to Mesenchymal Transition Activator ZEB1 Regulates Wound Angiogenesis and Closure in a Glycemic Status–Dependent Manner. Diabetes 68(11), 2175-2190 (IF: 9.46)

Choudhary, Saynaz A., N. Bora, D. Banerjee, L. Arora, A.S. Das, R. Yadav, K.N. Klotz, D. Pal, A.N. Jha, S. Dasgupta (2019) A novel small molecule A2A adenosine receptor agonist, indirubin-3′-monoxime, alleviates lipid-induced inflammation and insulin resistance in 3T3-L1 adipocytes. Biochemical Journal 476.16: 2371-2391 (IF: 4.097).

2009-2017

D. Gallego-Perez‡, D. Pal‡, S. Ghatak‡, V. Malkoc, N. Higuita-Castro, S. Gnyawali, L. Chang, W. Liao, J. Shi, M. Sinha, K. Singh, E. Steen, A. Sunyecz, R. Stewart, J. Moore, T. Ziebro, R. Northcutt, M. Homsy, P. Bertani, W. Lu, S. Roy, S. Khanna, C. Rink, V.B. Sundaresan, J. Otero, L.J. Lee, C.K. Sen (2017) Topical tissue nano-transfection mediated non-viral stroma reprogramming and rescue. Nature Nanotechnology 12 (10): 974-979. (‡equal contributor) [This article was highlighted in different journals including Science Translational Medicine, JAMA]. (IF: 39.213).

K. Singh, D. Pal, M. Sinha, S. Ghatak, S. Gnyawali, S. Khanna, S. Roy, C.K. Sen (2017) Epigenetic modification of microRNA-200b contributes to diabetic vasculopathy. Molecular Therapy 25 (12): 2689-2704 (IF: 11.454).

S. Gnyawali, K. Blum, D. Pal, S. Ghatak, S. Khanna, S. Roy, C.K. Sen (2017) Retooling laser speckle contrast analysis algorithm to enhance non-invasive high resolution laser speckle imaging of cutaneous microcirculation. Scientific Reports 7: 41048 (IF: 5.228).

D. Pal, S. Dasgupta, R. Kundu, S. Maitra, G. Das, S. Mukhopadhyay, S. Ray, S.S. Majumder, S. Bhattacharya (2012). Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance. Nature Medicine 18 (8): 1279-1285. [This article was highlighted in different journals including Cell, Nature Medicine, Nature Chemical Biology, Nature Immunology, Diabetes, Science Signaling]. (IF: 53.4).

S. Seal, P. Chatterjee, S. Bhattacharya, D. Pal, S. Dasgupta, R. Kundu, S. Mukherjee, S. Bhattacharya, M. Bhuyan, P.R. Bhattacharyya, G. Baishya, N.C. Barua, P.K. Baruah, P.G. Rao, S. Bhattacharya (2012) Vapor of volatile oils from Litsea cubeba seed induces apoptosis and causes cell cycle arrest in lung cancer cells. PLoS ONE 7 (10): e47014. (IF: 3.234).

S. Dasgupta, S. Bhattacharya, S. Maitra, D. Pal, S.S. Majumdar, A. Datta, S. Bhattacharya (2011) Mechanism of lipid induced insulin resistance: Activated PKCe is a key regulator. Biochimica et Biophysica Acta (Molecular Basis of Disease) 1812 (4): 495-506. (IF: 5.158)

P. Saha, S. Majumdar, D. Pal, B.C. Pal, S.N. Kabir (2010) Evaluation of spermicidal potential of Mi-saponin A. Reproductive Science 17 (5): 5454-64. (IF: 2.429).

D. Pal, P. Chakraborty, H.N. Ray, B.C. Pal, S.N. Kabir (2009) Acaciaside-B enriched fraction of Acacia auriculiformis is a prospective spermicide with no mutagenic property. Reproduction 138 (3): 453-62. (IF: 3.184).

D. Patra, S. Roy, P. Ramprasad, D. Pal* (2024). Next-generation therapies for type 2 diabetes mellitus Functional Smart Nanomaterials and Their Theranostics Approaches. Publisher: Springer Nature Singapore. ISSN 3004-8281.

M. Kalia, K. Bhavya, D. Pal* (2024). Tumor Microenvironment Regulates Immune Checkpoints: Emerging Need of Combinatorial Therapies Current Tissue Microenvironment Reports. Publisher: Springer International Publishing. ISSN 2662-4079. (IF: 3)

D. Patra, B. Kumari, P. Ramprasad, M. Kalia, D. Pal* (2023). Anti-cancer drug molecules targeting cancer cell cycle and proliferation. Advances in Protein Chemistry and Structural Biology. Publisher: Academic Press, Elsevier. ISSN 1876-1623. (IF: 5.447)

L. Arora, M. Kalia, D. Pal.* (2022). Role of macrophages in cancer progression and targeted immunotherapies. Advances in Protein Chemistry and Structural Biology. Publisher: Academic Press, Elsevier. ISSN 1876-1623. (IF: 5.447)

L. Arora, M. Kalia, B. Kumari,D. Pal* (2023) Oxidative stress: source of cellular plasticity and tumor heterogeneity. Book: “The Role of Reactive Oxygen Species in Health and Disease”. Nova Science Publisher, New York, USA

D. Pal* (2020) Chapter VIII:  miRNAs in diabetic wound healing. Wound Healing, Tissue Repair, and Regeneration in Diabetes (Book): Page 149-166.  Publisher: Academic Press, Elsevier.

D. Pal, S. Ghatak, C.K. Sen (2015) Book Chapter III: Epigenetic Modification of MicroRNAs (Page 77-109). Book: MicroRNA in Regenerative Medicine (Edited by: Chandan K. Sen). Publisher: Academic Press Elsevier, New York, USA (ISBN: 978-0-12-405544-5).

• Mantipally Manohar, Gundla Rambabu, D. Pal, Kumari Bhavya Badavath Vishnu Nayak. 2-Amino-4H-Pyran coupled imidazo[1,2-a] pyridine Compounds, compositions and method of synthesis thereof. Patent no. 202111040855 dated 09.09.2021. -Filled

• C. K. Sen, L. James Lee, D. Gallego-Perez, D. Pal, S. Ghatak. A methodology to directly reprogram skin tissue into blood vessels for applications in angiogenic therapies. Ref. No. IDF-029154 dated 26.12.2016. Meunier Carlin & Curfman LLC, Atlanta, GA, USA

• D Gallego-Perez, LJ Lee, D Pal, S Ghatak, C Sen. Compositions and methods for reprogramming somatic cells into induced vasculogenic cells. US Patent App. 16/471,808 dated 16.04.2020.

• Invited talk on “Adaptive cellular reprogramming at pathophysiological condition” at International Conference on Biomaterials, Regenerative Medicine And Devices (BIO-Remedi 2022) held on Dec 15th -18th 2022 organized by IIT Guwahati.

• Invited talk on “Tissue reprogramming with advanced materials: A new era in Regenerative medicine” at International Conference on Smart Materials for Sustainable Technology -II (SMST – 2022) organized jointly by IIT Bombay and IIT BHU Varanasi, held at IIT Bombay from 13-16th October 2022.

• Oral presentation on “Attenuation of lung tumor growth and angiogenesis by targeted delivery of lipid nanoparticle formulations” in the UK-India Interdisciplinary Workshop on Advanced Biomaterials and Biosensors (ABB-2018) organized jointly by the Cardiff University, UK and Indian Institute of Technology Ropar (IIT Ropar) held at Center for Biomedical Engineering, IIT Ropar during 13-15 November 2018

• Oral presentation on “Vasculogenic reprogramming of skin fibroblasts by anti-sense oligonucleotide inhibition of miRNA-200b rescuing diabetic wound angiogenesis” in NANOBIOTECK – 2018 organized by Indian Society of Nanomedicine (ISNM) at All India Institute of Medical Sciences (AIIMS), New Delhi, India, jointly hosted by AIIMS, New Delhi and IIT, New Delhi in partner with Department of Biotechnology (DBT) and Department of Science & Technology (DST), Government of India and National Innovation Foundation during October 24-27, 2018.

• Invited lecture on “Epigenetic Modification of miRNA 200b contributes to diabetic Vasculopathy” at 8th Professor R.N. Chakravarti Memorial Oration CME on “Multi-omics approaches to Disease” organized by the Department of Experimental Medicine and Biotechnology, PGIMER-Chandigarh, India on October 1, 2018.

Invited for a short story talk under the program of “Yuva Chikitsak Shodhkarta”on miR-200b davayee par shodh-madhumeh rogiyon ke liye upyogi which was recorded on September 7, 2018 at 11:00 AM and broadcasted in the radio on September 13, 2018 at 4:05 PM by All India Radio, Jalandhar, India

• Invited lecture on “Cellular plasticity in diabetic wound: a new perspective” at AAPI Global Healthcare Summit 2017 organized by American Association of Physicians of Indian Origin (AAPI) held at Calcutta Medical College & Hospital, Kolkata, India during December 28-31, 2017.

• Oral presentation on “miR-200b: A potential therapeutic target for diabetic wound healing” in the “Young Investigators Research Competition” at AAPI Global Healthcare Summit 2017 organized by American Association of Physicians of Indian Origin (AAPI) held at Calcutta Medical College & Hospital, Kolkata, India during December 28-31, 2017.

• Oral presentation on “Formulation of lyophilized lipid-nanoparticles conjugated with anti-miRNA: a potential targeted therapeutic molecule” at NANOBIOTECK – 2017 organized by Indian Society of Nanomedicine at Convention Centre, KTDC – Samudra, Trivandrum, India during December 6-8, 2017.

• Oral presentation on “Nanochannel-based electroporation assisted tissue reprograming and repair” in 7th International Conference on Tissue Engineering & Regenerative Medicine at Barcelona, Spain during October 02-04, 2017

• Presented a poster on “Nanochannel-based electrotransfection assisted in-vivo reprogramming of skin fibroblasts to hypermetabolic brown-like or beige adipocytes” in 9th Annual Translational to Clinical (T2C) Regenerative Medicine and Wound Care Conference at The Ohio State University Wexner Medical Center, Ohio, USA during March 17-19, 2016.

• Poster presentation on “Direct reprogramming of fibroblast to endothelial by nano-electroporation technology” in 20^th Annual Surgery Research Conference at The Ohio State University Wexner Medical Center, Ohio, USA on May 21, 2015 [Best Poster Award]

• Presented a poster and delivered a poster talk on “Nanochannel-based electrotransfection assisted reprograming of skin cells in vivo” in the International H3C: Health Sciences Innovation Conference jointly organized by The Ohio State University, Ohio, USA and All India Institute of Medical Science, New Delhi, India held at the Hotel Taj Palace, Mumbai during January 15-17, 2015. [Poster selected as a TOP 20 poster presenter at the Conference]

• Oral presentation on “Acaciaside-B-enriched fraction exerts spermicidal as well as anti-HIV activity with wide margin of safety” in 14th World Congress of Gynecological Endocrinology which was held at Piazza Auda, Florence, Italy during March 4-7, 2010.

• Poster presented on Recent Advances and Challenges in Reproductive Health Research at 17th Annual Meeting of the Indian Society for the Study of Reproductive and Fertility (ISSRF) which was held in ICMR, New Delhi during February 19-21, 2007