Seminar: Computational Modeling of Bone’s Adaptation to Mechanical Environment

Mr. Abhishek Kumar Tiwari (a Research Scholar with School of Mechanical, Materials & Energy Engineering at IIT Ropar) will deliver a seminar as a requirement of his comprehensive examination. You are invited to attend the seminar. The details are as follows:

Title: Computational Modeling of Bone’s Adaptation to Mechanical Environment

Date: Friday, 05 April 2013

Time: 10:00 AM (30-minute presentation followed by question/answer session)

Venue: L-2

Abstract:

Bone adapts to mechanical environment. Metabolic bone disorders such as osteoporosis or bone/muscle disuse (as in individuals with a physical disability or after a prolonged space flight) causes bone loss making the bone more susceptible to fracture. Prevention and treatment of the bone loss is a major challenge. A few studies have found that the mechanical loading of bone can prevent and cure such bone loss. In-vivo animal studies have also concluded that elevated mechanical strain in bone induces new bone formation.
However, the exact relationship between the mechanical environment and the new bone formation is not known. For example, new bone does not
form always at the site of elevated strain. The aim of the present study is to assimilate the major findings from the in-vivo models and build a robust computer model that will fit most of the experimental data available in the literature. The model will also be inverted to predict the loading regimen required for a prescribed new bone formation. This computer model will be useful in identifying therapeutic physical intervention required to prevent and treat the bone loss.

The following colleagues have kindly agreed to act as external examiners:
(i) Dr. Namrata Gundiah, Assistant Professor, Department of Mechanical Engineering, Indian Institute of Science, Bangalore.
(ii) Dr. Nirmal Raj Gopinathan, Assistant Professor, Department of Orthopaedics, Postgraduate Institute of Medical Education and Research
(PGIMER), Chandigarh.

The Doctoral Scrutiny Committee (DSC) members are as follows:
Coordinator, SMMEE (ex-officio member),
Dr. Anupam Agrawal,
Dr. Deepti R. Bathula,
Dr. Subhendu Sarkar,
Dr. Navin Kumar (Co-supervisor), and
Dr. Jitendra Prasad (Co-supervisor and convenor of the committee)